msbB deletion confers acute sensitivity to CO2 in Salmonella enterica serovar Typhimurium that can be suppressed by a loss-of-function mutation in zwf

Abstract Background Pathogens tolerate stress conditions that include Schrader Valve low pH, oxidative stress, high salt and high temperature in order to survive inside and outside their hosts.Lipopolysaccharide (LPS), which forms the outer-leaflet of the outer membrane in Gram-negative bacteria, acts as a permeability barrier.The lipid A moiety of

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Bovine Transcription Factor POU Class 2 Homeobox 1 (POU2F1/Oct1) Protein Promotes BoHV-1 Replication in MDBK Cells

Bovine herpesvirus type 1 (BoHV-1) causes severe diseases in bovine species and great economic burden to the cattle industry worldwide.Due to its complex life cycle, many host factors that affect BoHV-1 replication remain Lunge Line to be explored.To understand the possible roles that the Oct1 cellular protein could play in this process, we first c

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Theranostic Quantum Dots for Crossing Blood-Brain Barrier in vitro and Providing Therapy of HIV-associated Encephalopathy

The blood-brain barrier (BBB) is a complex physiological checkpoint that restricts the free diffusion of circulating molecules from the blood into the central nervous system (CNS).Delivering of drugs and other active agents across the blood brain barrier (BBB) is one of the major technical challenges faced by scientists and medical practitioners.Th

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